1287 – King Alfonso III- Isla Del Rey.
1711 – 1st Hospital erected under Admiral John Jennings, Commander of the Mediterranean.
1713 – Treaty of Utrecht 1st occupation, Governor Richard Kane – Bloody Island.
1756 – French domination – Ille du Roi.
1763 – Treaty of Paris- 2nd British occupation.
1771 – Governor General Moystin. 1st stone laid by Baron Peter Dennis, Admiral of the Mediterranean fleet.
1776- Hospital building finalized.
1781 – Hospital dismantled by Duke of Crillon.
1782 – Treaty of Versailles – 1st Spanish occupation.
1784 – Building repairs and addition of Chapel San Carlos.
1798 – 3rd British occupation
1802 – Peace treaty of Amiens. Conquerors right.
1821 – Yellow fever epidemic – Lazareto Island.
1830 – Military hospital during the French Wars (African conquests).
1833 – American Naval workshop and store depot.
1840 – Coal base for the French.
1888 – Basilica Paleocristiana unearthed under General Hipólito Llorente
1906 – South wing restored, copper plaque discovered commemorating completion of hospital in 1776.
1964 – Hospital transferred to C. Vasallo in Mahón town.
1974 – Town Council offers Island to the Spanish Government to build a Parador.
1979 – Hospital and inside garden are declared National Historical & Artistic Monument.
1985 – Property of the town Council of Mahón. One of the ideas propose was to build a 5 star hotel
2004 – Association Friends of the Hospital Island formed.
2005 – The Association converted into a Foundation